Anterior cingulate cortex and its input to the basolateral …
Jul 16, 2018 · Here, we show that the anterior cingulate cortex (ACC) and its input to the basolateral nucleus of amygdala (BLA) contribute to innate fear response to a predator odor in mice. Optogenetic...
Anterior cingulate cortex dysfunction underlies social deficits in
Jul 22, 2019 · We demonstrate that structural and functional impairments occur in glutamatergic synapses in the pyramidal neurons of the anterior cingulate cortex (ACC) in mice with a mutation in Shank3, a...
Anterior cingulate cortex-related functional hyperconnectivity ...
May 4, 2024 · Grin2b -mutant mice with a patient-derived C456Y mutation (Grin2bC456Y/+) show sensory hypersensitivity to mechanical, thermal, and electrical stimuli through supraspinal mechanisms. c-fos and...
Anterior cingulate inputs to nucleus accumbens control the social ...
Jan 8, 2021 · To address this topic, we optimized a protocol for the social transfer of pain behavior in mice and compared the ACC-dependent neural circuitry responsible for this behavior with the ACC neural circuitry required for the social transfer of two related behavioral states: analgesia and fear.
Cortical circuits modulate mouse social vocalizations
Sep 29, 2023 · We also found that when neural activity in the ACC is optogenetically suppressed, mice produce fewer syllables and initiate fewer songs in the presence of female mice. These results elucidated a possible function for ACC in initiating songs and propose the ACC as an important node in the USV-controlling network.
Chemogenetic silencing of neurons in the mouse anterior …
Oct 15, 2020 · The anterior cingulate area (ACC) is an integral part of the prefrontal cortex in mice and supports cognitive functions, including attentional processes, motion planning and execution as well as remote memory, fear and pain. Previous anatomical and functional imaging studies demonstrated that the ACC is interconnected with numerous brain ...
Whole-brain mapping of efferent projections of the anterior …
In the present study, we examined the continuous axonal outputs of the ACC in the whole brain of adult male mice. We used the virus anterograde tracing technique and an ultrahigh-speed imaging method of Volumetric Imaging with Synchronized on-the-fly-scan and Readout (VISoR).
Visual Sequences Drive Experience-Dependent Plasticity in Mouse ...
Sep 15, 2020 · The prefrontal anterior cingulate cortex (ACC) responds to visual stimuli, yet little is known about if and how visual experience modifies ACC circuits. We find that mouse ACC exhibits sequence plasticity, but in contrast to V1, the plasticity expresses as a change in response timing, rather than a change in response magnitude.
Anterior cingulate cortex provides the neural substrates for …
Jul 17, 2024 · Here, we tracked ACC activity in male mice performing go/no-go auditory discrimination tasks with manipulated stimulus-reward contingencies. Individual ACC neurons integrate the outcome...
Mediodorsal thalamus-projecting anterior cingulate cortex …
Oct 23, 2023 · By combining single-unit recordings and analysis of neural trajectory decoding, we demonstrated the dynamics of anterior cingulate cortex (ACC) neural activity changes synchronously with the harm avoidance performance of mice. In addition, ACC neurons projected to the mediodorsal thalamus (MDL) to modulate the harm avoidance behavior.