Akt Antibody | Cell Signaling Technology
Akt, also referred to as PKB or Rac, plays a critical role in controlling cell survival and apoptosis (1-3). This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase (2,3).
PI3K Akt 通路 | Cell Signaling Technology
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
Akt/PKB signaling pathway - Wikipedia
Activated Akt mediates downstream responses, including cell survival, growth, proliferation, cell migration and angiogenesis, by phosphorylating a range of intracellular proteins. The pathway is present in all cells of higher eukaryotes and is highly conserved.
PI3K Akt Pathway - Cell Signaling Technology
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
AKT/PKB Signaling: Navigating the Network - Cell Press
Studies of the AKT signaling network using increasingly sophisticated genetic, pharmacological, cell biological, and biochemical approaches have revealed the complex wiring of this branching and looping network and its intimate regulatory links to other cellular signaling networks.
Akt 信号转导 | Cell Signaling Technology
Cell Signaling Technology 的磷酸化 Akt 产品和资源，包括产品引用、教育视频和渠道、产品选择工具和对比数据
AKT/PKB Signaling: Navigating Downstream - Cell Press
2007年6月29日 · In response to growth factors, Akt signaling regulates nutrient uptake and metabolism in a cell-intrinsic and cell-type-specfic manner through a variety of downstream targets. One of the most important physiological functions of Akt is to acutely stimulate glucose uptake in response to insulin.
AKT kinases as therapeutic targets | Journal of Experimental
2024年11月29日 · Akt, also known as protein kinase B (PKB), is a 57-kDa integral kinase and signaling node that belongs to the protein kinase A, kinase G, and kinase C (AGC) superfamily of serine/threonine kinases, which includes the ribosomal S6 protein kinase and serum-glucocorticoid regulated kinases (SGK) [] Under conditions of homeostasis, Akt responds to extracellular cues by positively regulating cell ...
Akt Kinase Activation Mechanisms Revealed Using Protein ... - Cell …
These results provide a new framework for understanding how Akt is controlled in cell signaling and suggest distinct functions for differentially modified Akt forms.
AKT/PKB Signaling: Navigating the Network - ScienceDirect
2017年4月20日 · Studies of the AKT signaling network using increasingly sophisticated genetic, pharmacological, cell biological, and biochemical approaches have revealed the complex wiring of this branching and looping network and its intimate …