The life cycle of Brucella within host cells. During infection ...
During infection, Brucella first invade the host cells (①), form Brucella-containing vacuoles (BCVs) (②), and undergo fusion with the lysosome in a controlled manner (③). In this step, about...
Organization of the branched respiratory chain of Brucella. CI, complex …
In the intracellular pathogen Brucella, the LuxR homolog VjbR has been shown to regulate the expression of virulence factors acting at early stages of the intracellular infection and, directly or...
The ‘ins and outs’ of Brucella intracellular journey
2024年4月1日 · Brucella engages in a complex intracellular cycle within the host cell. This cycle involves a series of interactions between its membrane-bound vacuole and various cellular pathways, including endocytic, secretory, and autophagic pathways. Once internalized, the bacteria are individually enclosed in a Brucella -containing vacuole (BCV).
The Brucella Cell Envelope - PMC - PubMed Central (PMC)
We review distinct features of the Brucella envelope, highlighting a conserved regulatory system that links cell cycle progression to envelope biogenesis and cell division.
The Intracellular Life Cycle of Brucella spp
2019年3月8日 · Upon entry into host cells, Brucella organisms undergo a complex, multistage intracellular cycle in which they sequentially traffic through, and exploit functions of, the endocytic, secretory, and autophagic compartments via type IV secretion system (T4SS)-mediated delivery of bacterial effectors.
Brucella – Habitat, Morphology, Pathogenesis, Treatment
2024年11月30日 · Brucellosis is a complex infection with a wide variety of clinical presentations. The disease’s severity and duration depend largely on the Brucella species involved. Each species tends to cause a distinct clinical course, and the infection can range from acute to …
Diagrammatic representation of the Brucella cell envelope. The …
Brucella lipid A contains an unusual very-long-chain fatty acid (VLCFA). Cyclic β-1,2-glucans are synthesized by the inner membrane protein Cgs and then transported to the periplasm by the...
Brucella Bacteria Classification, Characteristics, Causes/Treatment
Named after David Bruce who first isolated the organism in 1887, Brucella bacteria is a genus that consists of ten (10) species which can be found in terrestrial and marine animals. They are facultative intracellular pathogens responsible for a contagious infection known as brucellosis. The ten species that belong to this genus include:
Brucella Morphology, Gram Staining, and Clinical Implications
2024年7月31日 · Brucella species are small, non-motile, Gram-negative coccobacilli, typically measuring between 0.5 to 0.7 micrometers in width and 0.6 to 1.5 micrometers in length. Their shape is somewhat variable, ranging from short rods to more rounded forms, which can sometimes complicate microscopic identification.
Brucella - Medical Microbiology - NCBI Bookshelf
Brucellosis is a zoonosis, acquired from handling of infected animals or consuming contaminated milk or milk products. Exposure is frequently occupational. The disease is now uncommon in the United States and Britain but common in the Mediterranean and Arabian Gulf regions, Latin America, Africa, and parts of Asia.