7.13C: Homologs, Orthologs, and Paralogs - Biology LibreTexts
2024年11月23日 · A homologous gene (or homolog) is a gene inherited in two species from a common ancestor. While homologous genes can be similar in sequence, similar sequences are not necessarily homologous. Orthologous are homologous genes where a gene diverges after a speciation event, but the gene and its main function are conserved.
Sequence homology - Wikipedia
Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.
Protein remote homology detection and structural alignment
2023年9月7日 · Once structurally similar proteins have been identified, DeepBLAST can structurally align proteins using only sequence information by identifying structurally homologous regions between...
Sequence similarity searching, typically with BLAST, is the most widely used and most reliable strategy for characterizing newly determined sequences. Sequence similarity searches can identify “homologous” proteins or genes by detecting excess similarity— statistically significant similarity that reflects common ancestry.
Homology - Site Guide - NCBI
A collection of related protein sequences (clusters), consisting of Reference Sequence proteins encoded by complete prokaryotic and organelle plasmids and genomes. The database provides easy access to annotation information, publications, domains, …
An introduction to sequence similarity ("homology") searching
Sequence similarity searches can identify "homologous" proteins or genes by detecting excess similarity- statistically significant similarity that reflects common ancestry. This unit provides an overview of the inference of homology from significant similarity, and introduces other units in this chapter that provide more details on effective ...
Automated selection of homologs to track the evolutionary …
2018年11月19日 · Homologous protein sequences are those with a common evolutionary origin. There are two types of protein homologs, depending on how they originated: paralogs, derived from a gene duplication event, and orthologs, originated from a speciation event .
一叶知因丨基因科普之 Homologous ＆ Analogous - 健康界
2021年3月31日 · 一般来说，如果两条基因序列相似性达80% ，就可以把它们称为“同源基因（homologous gene）”，比如比如人的NDUFV3基因，和黑猩猩的NDUFV3基因，还有小鼠的NDUFV3基因，名称拼写一样且序列相似性也比较高，它们可以称为同源基因。
omologous proteins share common functions, but sometimes they do not. Our ability to characterize the biological properties of a protein based on sequence data alone stems a. most exclusively from properties conserved through evolutionary time. Predictions of common properties for non-homologous proteins—s.
同源蛋白质(homologousproteins) - 百度百科
来自不同种类生物、而序列和功能类似的蛋白质。