Itraconazole (oral route) - Mayo Clinic
2024年2月1日 · Children—Use and dose must be determined by your doctor. For onychomycosis of the fingernails: Adults—200 milligrams (mg) 2 times a day for 1 week, followed by a no treatment period of 3 weeks, then 200 mg 2 times a day for 1 week.
Efficacy and safety of itraconazole use in children - PubMed
Current dosing regimens for itraconazole are effective, safe, and versatile for use in superficial fungal infections in children, particularly tinea capitis. Good efficacy rates have been noted in both Trichophyton and Microsporum tinea capitis infections.
Itraconazole Dosage Guide + Max Dose, Adjustments - Drugs.com
2023年8月4日 · Detailed Itraconazole dosage information for adults and children. Includes dosages for Vaginal Candidiasis, Oral Thrush, Onychomycosis - Toenail and more; plus renal, liver and dialysis adjustments.
ITRACONAZOLE Paediatric - PedMed
2022年7月3日 · ITRACONAZOLE (Paeds) (Sporanox) Mechanism of action: Azole antifungal Ref: 6, 44, 270 Last update: 2022-07-03: capsule: 100 mg oral solution: 10 mg/mL: Children: 5 mg/kg/dose PO once to twice daily. Usual maximum: 200 mg BID. Allergic bronchopulmonary aspergillosis in cystic fibrosis: 5 mg/kg/dose PO once to twice daily.
Itraconazole - DermNet
The dose of itraconazole in children is usually 5 mg per kg body weight per day to maximum 200 mg per day, but is reserved for exceptional circumstances. Itraconazole appears to be a relatively safe drug. Side effects, usually minor, are more likely during a prolonged course of treatment.
Antifungal agents for common paediatric infections - PMC
Clinical trials and case series using itraconazole to treat tinea capitis have shown it to be effective (approximately 90% of the time) for infections caused by either Trichophyton and Microsporum species (33–37). Few side effects were seen in most studies using 3 mg/kg/day to 5 mg/kg/day for four to six weeks.
Systemic antifungal therapy for tinea capitis in children - PMC
Some evidence based on a few studies shows that oral itraconazole at doses according to the child's weight for two to six weeks is effective and safe for tinea capitis caused by T. violaceum (two weeks of treatment) and M. canis (six weeks of treatment).
Efficacy and safety of itraconazole use in children
Itraconazole is generally safe and effective against most fungal organisms causing superficial and systemic infection in children. Dosages of 5 mg/kg/d have given a wide range of successful antifungal treatment, with few serious side effects being noted despite a wide range of underlying physiologic states.
Itraconazole | Drugs | BNFC | NICE
Child 2.5 mg/kg twice daily, to be started before transplantation or before chemotherapy (taking care to avoid interaction with cytotoxic drugs) and continued until neutrophil count recovers, safety and efficacy not established.
Itraconazole Dosing and Drug Monitoring at a Tertiary Children…
Achieving the recommended target serum itraconazole trough concentration of ≥0.5 mg/L is challenging in children because of variation in itraconazole pharmacokinetics with age. We studied itraconazole use and treatment outcomes in a tertiary children's hospital.
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