Leukocidin - Wikipedia
A leukocidin is a type of cytotoxin created by some types of bacteria (Staphylococcus). It is a type of pore-forming toxin. The model for pore formation is step-wise. First, the cytotoxin's "S" subunit recognizes specific protein-containing receptors, or an integrin on the host cell's surface.
Leukocidins: staphylococcal bi-component pore-forming …
2017年4月19日 · Staphylococcal leukocidins are a family of bi-component pore-forming toxins that are important virulence factors. During the past five years, cellular receptors have been identified for all of...
Leukocidins: Staphylococcal bi-component pore-forming toxins …
The staphylococcal leukocidins are a family of bi-component pore-forming toxins that are important virulence factors. During the past five years, cellular receptors have been identified for all of the bi-component leukocidins.
The cell envelope of Staphylococcus aureus selectively ... - Nature
2021年10月26日 · Intriguingly, one of the leukocidins, Leukocidin AB (LukAB), is found associated with the bacterial cell envelope in addition to secreted into the extracellular milieu.
Studying Staphylococcal Leukocidins: A Challenging Endeavor
2020年4月15日 · A major group of S. aureus virulence factors is the bi-component β-barrel pore-forming toxins, also known as leukocidins. These pore-forming toxins target specific cells of the innate and adaptive immune system by interacting with …
Leukocidin - an overview | ScienceDirect Topics
Leukocidin interacts with the membrane phospholipid and causes depolarization, increased permeability, and cell death. Local secretion of leukocidin may appear to confer an advantage to the staphylococcus by killing leukocytes and thereby preventing phagocytosis and …
2017年4月19日 · Staphylococcal leukocidins are a family of bi‐component pore‐forming toxins that are important virulence factors. During the past five years, cellular receptors have been identified for all of...
Leukocidin - an overview | ScienceDirect Topics
Leukocidins are cytolytic exotoxins that destroy white blood cell lineages involved in both the innate and acquired immune responses (Frey, 2019). Innate immune cells like neutrophils and macrophages are common targets, and highly virulent bacteria (e.g., S. aureus) tend to make three to five leukocidins (Alonzo and Torres, 2014).
Leukocidins: staphylococcal bi-component pore-forming toxins ... - PubMed
Staphylococcal leukocidins are a family of bi-component pore-forming toxins that are important virulence factors. During the past five years, cellular receptors have been identified for all of the bi-component leukocidins.
Panton–Valentine leukocidin - Wikipedia
Panton–Valentine leukocidin (PVL) is a cytotoxin—one of the β-pore-forming toxins. The presence of PVL is associated with increased virulence of certain strains (isolates) of Staphylococcus aureus.
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