Microcirculation - Wikipedia
The microcirculation is the circulation of the blood in the smallest blood vessels, the microvessels of the microvasculature present within organ tissues. [1] . The microvessels include terminal arterioles, metarterioles, capillaries, and venules.
Structure and Function of Exchange Microvessels
The microvasculature consists of three types of small vessels: arterioles, capillaries, and venules. These microvessels form a network that regulates local blood perfusion and conducts blood–tissue exchange [262, 415] (Figure 1). Architecture of a microvascular bed.
Microvessel - an overview | ScienceDirect Topics
Microvessels are the major site for fluid and solute exchange between the blood and surrounding tissues. Gas transport which includes tissue oxygenation and inert gas clearance is highlighted in the article when microvessels have countercurrent arrangements.
Transcriptomic comparison of human and mouse brain microvessels …
2020年7月23日 · To identify genes for which microvessel, rather than parenchymal, expression drives species-specific enrichment, we filtered human- and mouse-enriched genes based on microvessel-enrichment in...
The Isolated Brain Microvessel: A Versatile Experimental Model …
Brain microvessels are primarily comprised of endothelial cells, but also include pericytes, pre-capillary arteriolar smooth muscle cells, astrocyte foot processes, and occasional nerve endings. These microvessels can be isolated from brain with a 3 h procedure, and the microvessels are free of brain parenchyma.
An easy-to-perform method for microvessel isolation and primary …
2024年6月30日 · Here, we developed a rapid and streamlined protocol for BEC isolation without using transgenic reporters, flow cytometry, and magnetic beads, which are essential for existing methods.
Frontiers | Isolation of Mouse Cerebral Microvasculature for …
2020年4月8日 · Here, we describe an optimized protocol to purify microvessels from the mouse cerebral cortex using mechanical homogenization and density-gradient centrifugation, while maintaining the structural integrity and functional activity of the BBB.
Engineered Microvessels for the Study of Human Disease
2016年10月21日 · Microvessels comprise capillaries, arterioles, and postcapillary venules, and function as resistance and transport vessels to regulate hydrodynamics and the exchange of nutrients and waste products within tissues. Histologically, arterioles contain only one or two layers of smooth muscle cells and a thin, poorly defined, tunica adventitia.
Microvessel - an overview | ScienceDirect Topics
Microvessels—the smallest functional unit of the CV system—consist of arterioles, capillaries, and venules. These vessels differ significantly from macrovessels with respect to architecture and cellular components.
Microvessel isolation protocol for RNA visualization and profiling
2024年10月26日 · Microvessel isolation has emerged as a versatile experimental model for investigating the dynamics of the BBB and the neurovascular unit (NVU). The NVU consists of endothelial cells,...