Hematopoietic stem cell - Wikipedia
Hematopoietic stem cells are essential to haematopoiesis, the formation of the cells within blood. Hematopoietic stem cells can replenish all blood cell types (i.e., are multipotent) and self-renew. A small number of hematopoietic stem cells can expand to generate a very large number of daughter hematopoietic stem cells.
Hematopoiesis from Multipotent Stem Cells - Thermo Fisher Scientific
Explore hematopoiesis from multipotent stem cells and find antibodies to detect some of its target proteins, including stem cell factor (SCF), IL-7, IL-15, and IL-2.
Frontiers | Hematopoietic Multipotent Progenitors and Plasma Cells ...
2021年4月14日 · In the adult mouse, all functional hematopoietic stem cell (HSC) activity is found within the Lin-Sca1+c-Kit+ (LSK) compartment, which comprises about 0.00125% of total BM cells. This small cellular population is itself subdivided into various subsets based on the expression of cell surface markers such as CD34, CD135 (Flk2/Flt3), CD150, and ...
Characterization and generation of human definitive multipotent ...
2020年12月1日 · We characterize the distinct molecular profiling between early primitive and definitive hematopoiesis in both human embryonic stem cell (hESC) differentiation and early embryonic development.
Hematopoiesis: Types of Haematopoietic stem cells, Process …
2020年7月7日 · These unipotential stem cells then multiply rapidly into the precursor of the destined specific mature blood cell. The typical process of hematopoiesis consists of the differentiation of the multipotential hematopoietic stem cell into either the common myeloid or lymphoid progenitor.
Induction of multipotential hematopoietic progenitors from …
2013年10月3日 · Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors
Induction of Multipotential Hematopoietic Progenitors from Human ...
2013年10月3日 · A strategy for making transplantable hematopoietic cells from human pluripotent cells involving transcription-factor-based induction of stem-cell-like properties in differentiated progenitors.
On Hematopoietic Stem Cell Fate: Immunity - Cell Press
2007年6月22日 · Multipotential hematopoietic stem cells (HSCs) maintain blood-cell formation throughout life. Here, Metcalf considers the origin and heterogeneity of HSCs, their ability to self-generate, and their commitment to the various hematopoietic lineages.
Hematopoiesis from Pluripotent Stem Cells - Thermo Fisher Scientific
Thus, every day, billions of new blood cells are produced in the body, each one derived from a single hematopoietic stem cell. Colony-stimulating factors, cytokines, and cytokine receptors provide signals that enable the survival and proliferation of the multipotential and mature hematopoietic cells [5].
Characterization and generation of human definitive multipotent ...
Definitive hematopoiesis generates hematopoietic stem/progenitor cells (HSPCs) that give rise to all mature blood and immune cells, but remains poorly defined in human. Here, we resolve human hematopoietic populations at the earliest hematopoiesis ...
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