PAMAM Dendrimers
Polyamidoamine (PAMAM) dendrimers are hyperbranched polymers with unparalleled molecular uniformity, narrow molecular weight distribution, defined size and shape characteristics and a multifunctional terminal surface.
A review on structural aspects and applications of PAMAM …
Dec 1, 2022 · PAMAM dendrimers are among the most widely explored family of dendrimers that contains a variable count of carbonyl and primary and tertiary amine groups in their internal branching network along with multifunctional active or passive terminal groups.
Poly(amidoamine) (PAMAM): An emerging material for …
Feb 1, 2016 · Poly (amidoamine) (PAMAM) dendrimers have received attention due to their large surface areas with high concentration of functional end groups to bind biological material. They are monodisperse and hyper-branched polymers which include active functional groups outside its …
New Advances in General Biomedical Applications of PAMAM Dendrimers
PAMAM (polyamidoamine) was introduced in 1985, by Donald A. Tomalia, as a new class of polymers, named ‘starburst polymers’. This important contribution of Professor Tomalia opened a new research field involving nanotechnological approaches.
Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to …
Apr 15, 2001 · Poly (amidoamine) (PAMAM) dendrimers are the first complete dendrimer family to be synthesized, characterized and commercialized. Based on this extensive activity, they are recognized as a unique new class of synthetic nanostructures.
Bioapplications of poly(amidoamine) (PAMAM) dendrimers in …
Mar 13, 2014 · Poly(amidoamine) (PAMAM) dendrimers are a novel class of spherical, well-designed branching polymers with interior cavities and abundant terminal groups on the surface which can form stable complexes with drugs, plasmid DNA, oligonucleotides, and antibodies.
Nanoscale Investigation of Generation 1 PAMAM Dendrimers
Jul 21, 2017 · Herein, we describe at uni-molecular level the interactions between poly (amidoamine) (PAMAM) dendrimers of generation 1 and the α-hemolysin protein nanopore, at acidic and neutral pH, and...
(PDF) Poly(amidoamine) (PAMAM) Dendrimers: Synthesis and Biological ...
May 20, 2020 · In this chapter, we present an overview of the synthesis of PAMAM dendrimers and their related biological applications as drugs, and as systems for delivering drugs, nucleic acids and imaging...
New Advances in General Biomedical Applications of PAMAM …
Directing groups to reach selective delivery in a specific organ is one of the advanced applications of PAMAM. In this review, structural and safety aspects of PAMAM and its derivatives are discussed, and some relevant applications are briefly presented.
Recent Advances in Preclinical Research Using PAMAM …
Poly (amidoamine) (PAMAM) dendrimers are repetitively branched, three-dimensional molecules, made of amide and amine subunits, possessing unique physiochemical properties.
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