Spleen | Lymphoid System - Histology Guide
The spleen is an encapsulated organ that filters blood and immunologically monitors blood. Capsule - dense connective tissue enclosing the organ. Trabeculae - connective tissue that extends inward from the capsule through which blood vessels enter the pulp.
Spleen histology: Location, functions, structure | Kenhub
2022年12月5日 · The spleen has a unique location, embryological development and histological structure that differs significantly from other lymphoid organs. Special histological features define several important functions of the spleen, such as filtering blood, maintaining immune response balance and recycling iron.
Histology of the spleen: structure and cellular distribution in …
1997年6月1日 · Since a great deal of experimental work on the immune system has been carried out in mice and rats, there is a 100 HISTOLOGY OF THE SPLEEN 101 wealth of knowledge about the structure and function of the different compartments in the rodent spleen.14-18 It is clear, however, that the human spleen differs widely from the rodent spleen; in ...
Normal Structure, Function, and Histology of the Spleen
The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells.
Structure and function of the spleen - Nature Reviews Immunology
2005年8月1日 · In this article, we discuss how splenic macrophages not only have a role in the recognition and uptake of pathogens by PATTERN-RECOGNITION RECEPTORS but also are involved in the structural...
Anatomy, Embryology, Histology and Physiology of the Spleen
The spleen is the largest lymphoid organ in the body and is interposed within the circulatory system. The spleen has multiple functions in the human body: 1. It clears the circulation of micro-organisms, par- ticulate antigens and other foreign material. 2. It makes the majority of antibodies and enhances cellular immunity to antigens. 3.
Anatomy and Physiology of the Spleen - ScienceDirect
2019年1月1日 · The spleen serves important functions as a secondary lymphoid tissue, contributing through phagocytosis and orchestration of humoral and cellular immunity. 5 The spleen is also associated with multiple nonimmunologic functions, serving as the differentiation site for platelets, reticulocytes, and monocytes; the reservoir for granulocytes and ...
Histology of the spleen: structure and cellular distribution in the ...
This review describes the different compartments of the spleen as well as their cellular contents. Special emphasis is given to those structures that cause the most difficulties in surgical pathology.
Spleen: Development, anatomy and reactive lymphoid proliferations
2021年3月1日 · Benign and infectious processes may show characteristic pathology in the spleen. The unique architecture of the spleen enables it to play a key role in the interactions between the circulatory, reticuloendothelial and immune systems.
Structure and function of the immune system in the spleen
2019年3月2日 · The physical organization of the spleen allows it to filter blood of pathogens and abnormal cells and facilitate low-probability interactions between antigen-presenting cells (APCs) and cognate lymphocytes. APCs specific to the spleen regulate the T and B cell response to these antigenic targets in the blood.