Regulatory T cell and macrophage crosstalk in acute lung ... - Nature
2023年1月16日 · Regulatory T cells (Tregs) and macrophages are responsible for acute lung injury (ALI) progression through pro-/anti-inflammatory cell balance. Tregs and macrophages …
Regulatory T cells in lung disease and transplantation - PMC
Regulatory T (Treg) cells have an important role in maintaining immune balance in the body through immune regulation and immunosuppression. Treg cells are a subpopulation of CD4 + …
Global characterization of T cells in non-small-cell lung ... - Nature
2018年6月25日 · The gene signature of those activated tumor Tregs, which included IL1R2, correlated with poor prognosis in lung adenocarcinoma. Our study provides a new approach …
Regulatory T cells: Supporting lung homeostasis and promoting ...
2024年5月1日 · Tregs suppress immune responses, prevent autoimmunity, and serve to regulate pro-inflammatory immune cells. Within the lung, Tregs act as mediators of immune tolerance, …
Interleukin-33 activates regulatory T cells to suppress innate γδ T ...
2020年9月28日 · Here we describe an unexpected function of ST2+ Treg cells in suppressing the innate immune response in the lung to environmental allergens without altering the adaptive …
Regulatory T Cells and Acute Lung Injury: Cytokines, Uncontrolled ...
2018年7月9日 · Regulatory T cells (Tregs) are a special type of T cell. It could restrict inflammation-induced tissue damage via multiple mechanisms indirectly, such as their anti …
Highlight of 2023: Tregs in the lungs - Wiley Online Library
2024年5月2日 · In 2023, several key papers have highlighted the capacity of lung Tregs to mediate tissue repair and to modulate the lung environment in response to self-antigen versus …
Th17/Treg Imbalance: Implications in Lung Inflammatory Diseases …
2022年12月31日 · Regulatory T cells (Tregs) and T helper 17 cells (Th17) are two CD4 + T cell subsets with antagonist effects. Th17 cells promote inflammation, whereas Tregs are crucial in …
Regulatory T-Cells as an Emerging Barrier to Immune Checkpoint ...
2021年6月1日 · Recent evidence suggests that regulatory T-lymphocytes (Tregs) serve as a central mediator of immune function in lung cancer, suppressing sterilizing immunity and …
The emerging role of regulatory T cells following lung ... - PubMed
Recent insights from animal models of lung transplantation have established that Tregs play a vital role in suppressing rejection and facilitating tolerance of lung allografts, and such …