XIAP - Wikipedia
X-linked inhibitor of apoptosis protein (XIAP), also known as inhibitor of apoptosis protein 3 (IAP3) and baculoviral IAP repeat-containing protein 4 (BIRC4), is a protein that stops apoptotic cell death.
XIAP Gene - GeneCards | XIAP Protein | XIAP Antibody
5 天之前 · XIAP (X-Linked Inhibitor Of Apoptosis) is a Protein Coding gene. Diseases associated with XIAP include Lymphoproliferative Syndrome, X-Linked, 2 and Lymphoproliferative Syndrome 2 . Among its related pathways are SMAC (DIABLO) binds to IAPs and TNF signaling .
XIAP - 百度百科
X连锁凋亡抑制蛋白(X-linked inhibitor of apoptosis protein,XIAP)是新发现的一个IAP家族中的主要成员，是IAP家族中最强的凋亡抑制因子，它可直接抑制caspases并可多途径调节细胞凋亡。
XIAP as a ubiquitin ligase in cellular signaling | Cell Death ...
2009年7月10日 · The ability of the vertebrate X-linked inhibitor of apoptosis (XIAP) protein to directly suppress apoptotic cell death pathways has been the subject of much research.
A potential role of X-linked inhibitor of apoptosis protein in ...
X-chromosome-linked inhibitor of apoptosis protein (XIAP) inhibits caspases and blocks apoptosis. XIAP can also function as a proapoptotic protein by promoting mitochondrial membrane permeabilization, which could be exploited for therapeutic benefits in cancer.
Subcellular localization of X-linked inhibitor of apoptosis protein ...
Regardless of potential pitfalls in assessing XIAP expression, strong evidence indicates that XIAP protein can be found in different subcellular compartments, cytoplasm, mitochondria and nucleus, further regulating diverse signaling pathways sustaining cancer hallmarks.
XIAP as a multifaceted molecule in Cellular Signaling
2022年6月4日 · Apoptosis - XIAP, X-linked inhibitor of apoptosis protein, is a member of the inhibitor of apoptosis protein (IAP) family known for its important conserved inhibitory effect on caspase activity....
Phenotype, genotype, treatment, and survival outcomes in …
We specifically examined 35 patients identified with missense mutations, resulting in variable expression of XIAP protein (reported to range from normal to absent).
Targeting XIAP for the treatment of malignancy | Cell Death ...
2005年12月2日 · Of these members, X-linked inhibitor of apoptosis protein (XIAP, also known as hILP, MIHA and BIRC4) and survivin have garnered the most attention as potential therapeutic targets.
XIAP gene - MedlinePlus
The XIAP gene provides instructions for making a protein that is found in many types of cells, including immune cells. Learn about this gene and related health conditions.