What is a Xenograft? | Taconic Biosciences
The term xenograft refers to a tissue or organ that is derived from a species that is different from the recipient of the specimen. They are powerful research tools in oncology as well as essential for treating wounds in the clinic.
Xenotransplantation - Wikipedia
Xenotransplantation (xenos- from the Greek meaning "foreign" or strange [1][2]), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. [3] . Such cells, tissues or organs are called xenografts or xenotransplants.
Patient-derived xenograft models in cancer therapy ... - Nature
2023年4月12日 · Patient-derived xenograft (PDX) models, in which tumor tissues from patients are implanted into immunocompromised or humanized mice, have shown superiority in recapitulating the characteristics...
Xenograft - an overview | ScienceDirect Topics
A xenograft is an inoculation of a tumor cell suspension or implantation of tissue pieces from a foreign species, in contrast to an allograft, in which the transplantable material is from the same species. Usually, human tumors are grafted into immunodeficient mice.
A human breast cancer-derived xenograft and organoid ... - Nature
2022年2月24日 · We report a bank of human patient-derived xenografts (PDXs) and matched organoid cultures from tumors that represent the greatest unmet need: endocrine-resistant, treatment-refractory and...
Definition of xenograft - NCI Dictionary of Cancer Terms
The transplant of an organ, tissue, or cells to an individual of another species.
Assessing the Science Base - Xenotransplantation - NCBI Bookshelf
Xenotransplants, or xenografts, are viewed as one solution to the growing problem of the inadequate supply of human organs and as a source of cells, tissues, and organs that show promise for treating a variety of human diseases. This chapter was drawn largely from the workshop Session I: Assessing the Science Base.